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O-anisamide derivatives

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专利名称:O-anisamide derivatives

发明人:HIROYA SATOH,MASAKATSU KOMURO,KOJI

MURAKAMI,KATSUYA AWANO

申请号:AU6867900申请日:20000901公开号:AU778282B2公开日:20041125

摘要:The invention provides o-anisamide derivatives and their addition salts effectivefor the prevention and/or therapy of metabolic diseases such as hyperlipidemia anddiabetes, in which peroxisome proliferator-activated receptor (PPAR) being intranuclearreceptor, in particular, human PPAR participates, as agonistic drugs thereon, andprocesses for preparing them. The invention relates to o-anisamide derivativesrepresented by a general formula (1) Äwherein R denotes a carboxyl group,

carboxymethyl group or CH2CHXCOY (here X denotes a mercapto group or S(O)nMe(n=0, 1 or 2) and Y denotes an amino group or hydroxyl group)Ü, their medicinallyacceptable salts, their hydrates, and processes for preparing them.

申请人:KYORIN PHARMACEUTICAL CO., LTD.

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