Indole derivatives and use thereof in medicines

专利名称：Indole derivatives and use thereof in

medicines

发明人：KOJI KAWAI,TAKUMI AOKI,SATOSHI

SAKAMI,MASAYUKI MAEDA,SHINYA UENO

申请号：AU2002224086申请日：20061019公开号：AU2002224086B8公开日：20020603

摘要：Indole derivatives represented by the general formula (I) or pharmacologicallyacceptable salts thereof, and pharmaceutical compositions (particularly d opioid receptoragonist) containing the same: (I) wherein R<1> is hydrogen, C1-5 alkyl, or the like; R<2> ishydrogen, hydroxyl, or the like; R<3> is hydrogen, hydroxyl, or the like; -Z- is a bridgehaving 2 to 5 carbon atoms; m is an integer of 0 to 3; n is an integer of 0 to 10; R<4> andR<5> are each fluoro, hydroxyl, or the like; R<9> is hydrogen, C1-5 alkyl, or the like; andR<10> and R<11> may be united to form O- or the like.

申请人：TORAY INDUSTRIES, INC

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